The nematode Caenorhabditis elegans as an integrated toxicological tool to assess water quality and pollution
Determination ofwater quality status in rivers is critical to establish a sustainable watermanagement policy. For this reason, over the last decades it has been recommended to perform integratedwater assessments that include water quantities and physicochemical, ecological and toxicological tests. However, sometimes resources are limited and it is not possible to perform large-scale chemical determinations of pollutants or conduct numerous ecotoxicological tests. To overcomethis problemwe use andmeasure the growth, as a response parameter, of the soil nematode Caenorhabditis elegans to assesswater quality in rivers. The C. elegans is a ubiquitous organismthat has emerged as an important model organism in aquatic and soil toxicology research. The Tunuyán River Basin [Province of Mendoza, Argentina] has been selected as a representative traditional water monitoring system to test the applicability of the C. elegans toxicological bioassay to generate an integrated water quality evaluation. Jointly with the C. elegans toxic assays, physicochemical and bacteriological parameters were determined for each monitoring site. C. elegans bioassays help to identify different water qualities in the river basin Multivariate statistical analysis [PCA and linear regression models] has allowed us to confirm that traditional water quality.
BIOASSAY ENVIRONMENTAL TOXICOLOGY WATER QUALITY THREATS